[et_pb_section fb_built=\u00bb1″ module_id=\u00bbunidadesmixtas\u00bb _builder_version=\u00bb4.2.1″ background_color=\u00bbrgba(0,0,0,0)\u00bb background_enable_image=\u00bboff\u00bb background_blend=\u00bbmultiply\u00bb custom_margin=\u00bb0px||||false|false\u00bb custom_padding=\u00bb0px||0px||true|false\u00bb][et_pb_row use_custom_gutter=\u00bbon\u00bb gutter_width=\u00bb1″ make_equal=\u00bbon\u00bb _builder_version=\u00bb4.2.1″ background_color=\u00bb#425059″ width=\u00bb100%\u00bb max_width=\u00bb2560px\u00bb module_alignment=\u00bbcenter\u00bb min_height=\u00bb150px\u00bb custom_margin=\u00bb0px||0px||false|false\u00bb custom_padding=\u00bb0px||0px|||\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb3.27.4″ custom_css_main_element=\u00bbdisplay: flex;||flex-direction: column;||justify-content: center;\u00bb][et_pb_post_title meta=\u00bboff\u00bb featured_image=\u00bboff\u00bb _builder_version=\u00bb4.2.1″ title_font=\u00bbOswald|300||on|||||\u00bb title_text_align=\u00bbcenter\u00bb title_text_color=\u00bb#425059″ title_font_size=\u00bb40px\u00bb background_color=\u00bb#ffffff\u00bb module_alignment=\u00bbcenter\u00bb custom_margin=\u00bb30px||30px||true|false\u00bb custom_padding=\u00bb7px||4px||false|false\u00bb border_width_top=\u00bb6px\u00bb border_color_top=\u00bb#ff9000″][\/et_pb_post_title][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00bb1″ make_equal=\u00bbon\u00bb use_custom_gutter=\u00bbon\u00bb gutter_width=\u00bb1″ specialty=\u00bbon\u00bb padding_top_bottom_link_1=\u00bbfalse\u00bb padding_top_bottom_link_2=\u00bbfalse\u00bb padding_left_right_link_1=\u00bbfalse\u00bb padding_left_right_link_2=\u00bbfalse\u00bb padding_right_2=\u00bb0px\u00bb padding_left_1=\u00bb20px\u00bb padding_left_2=\u00bb20px\u00bb module_class=\u00bbds-fullwidth-specialty\u00bb _builder_version=\u00bb4.2.1″ background_color=\u00bbrgba(174,186,193,0.15)\u00bb background_color_gradient_direction=\u00bb90deg\u00bb background_enable_image=\u00bboff\u00bb positioning=\u00bbnone\u00bb width=\u00bb90%\u00bb module_alignment=\u00bbcenter\u00bb custom_margin=\u00bb38px|0px||0px|false|false\u00bb custom_padding=\u00bb0px|0px|34px|0px|false|true\u00bb locked=\u00bboff\u00bb][et_pb_column type=\u00bb1_4″ _builder_version=\u00bb3.25″ custom_padding=\u00bb|||\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text _builder_version=\u00bb4.2.1″ text_font=\u00bb|600|||||||\u00bb text_line_height=\u00bb1.2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb|||on|||||\u00bb header_2_text_align=\u00bbleft\u00bb header_2_text_color=\u00bb#ffffff\u00bb header_2_font_size=\u00bb16px\u00bb header_2_letter_spacing=\u00bb1px\u00bb header_2_line_height=\u00bb1.1em\u00bb background_enable_color=\u00bboff\u00bb text_orientation=\u00bbcenter\u00bb custom_margin=\u00bb0px|0px|0px|0px|false|false\u00bb custom_margin_last_edited=\u00bboff|desktop\u00bb custom_padding=\u00bb0px|0px|0px|2px|false|false\u00bb custom_padding_last_edited=\u00bboff|desktop\u00bb border_width_top=\u00bb6px\u00bb border_color_top=\u00bb#425059″ locked=\u00bboff\u00bb custom_padding__hover=\u00bb|32px||\u00bb custom_margin__hover=\u00bb|||-8px\u00bb box_shadow_style__hover=\u00bbnone\u00bb box_shadow_style__hover_enabled=\u00bbnone\u00bb box_shadow_color__hover=\u00bbrgba(0,0,0,0.3)\u00bb box_shadow_color__hover_enabled=\u00bbrgba(0,0,0,0.3)\u00bb border_radii__hover=\u00bbon||||\u00bb border_radii__hover_enabled=\u00bbon||||\u00bb][\/et_pb_text][et_pb_text _builder_version=\u00bb4.2.1″ text_font=\u00bb|600|||||||\u00bb text_font_size=\u00bb12px\u00bb text_line_height=\u00bb1.2em\u00bb background_color=\u00bb#ffffff\u00bb module_alignment=\u00bbleft\u00bb custom_margin=\u00bb0px|0px|0px|0px|false|false\u00bb custom_margin_last_edited=\u00bboff|desktop\u00bb custom_padding=\u00bb4px||4px|20px|true|false\u00bb custom_padding_last_edited=\u00bboff|desktop\u00bb link_option_url=\u00bb#trayectoria\u00bb border_width_all=\u00bb1px\u00bb border_color_all=\u00bb#aebac1″ border_width_right=\u00bb0px\u00bb border_width_left=\u00bb0px\u00bb border_color_left=\u00bb#FF6600″ box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb0px\u00bb box_shadow_blur=\u00bb0px\u00bb locked=\u00bboff\u00bb border_width_left__hover_enabled=\u00bbon|hover\u00bb border_width_left__hover=\u00bb8px\u00bb box_shadow_blur__hover_enabled=\u00bbon\u00bb custom_padding__hover_enabled=\u00bbon|hover\u00bb custom_margin__hover=\u00bb|||-8px\u00bb box_shadow_blur__hover=\u00bb40px\u00bb border_color_left__hover_enabled=\u00bbon|hover\u00bb]<\/p>\n
TRAYECTORIA ACAD\u00c9MICA Y DE INVESTIGACI\u00d3N<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=\u00bb4.2.1″ text_font=\u00bb|600|||||||\u00bb text_font_size=\u00bb12px\u00bb text_line_height=\u00bb1.2em\u00bb background_color=\u00bb#ffffff\u00bb module_alignment=\u00bbleft\u00bb custom_margin=\u00bb0px|0px|0px|0px|false|false\u00bb custom_padding=\u00bb4px||4px|20px|true|false\u00bb link_option_url=\u00bb#investigacion\u00bb border_width_all=\u00bb1px\u00bb border_color_all=\u00bb#aebac1″ border_width_top=\u00bb0px\u00bb border_width_right=\u00bb0px\u00bb border_width_left=\u00bb0px\u00bb border_color_left=\u00bb#FF6600″ box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb0px\u00bb box_shadow_blur=\u00bb0px\u00bb locked=\u00bboff\u00bb border_width_left__hover_enabled=\u00bbon|hover\u00bb border_width_left__hover=\u00bb8px\u00bb box_shadow_blur__hover_enabled=\u00bbon\u00bb custom_padding__hover_enabled=\u00bbon|hover\u00bb custom_padding__hover=\u00bb|32px||\u00bb custom_margin__hover=\u00bb|||-8px\u00bb box_shadow_blur__hover=\u00bb40px\u00bb border_color_left__hover_enabled=\u00bbon|hover\u00bb]<\/p>\n
INVESTIGACI\u00d3N ACTUAL<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=\u00bb4.2.1″ text_font=\u00bb|600|||||||\u00bb text_font_size=\u00bb12px\u00bb text_line_height=\u00bb1.2em\u00bb background_color=\u00bb#ffffff\u00bb module_alignment=\u00bbleft\u00bb custom_margin=\u00bb0px|0px|0px|0px|false|false\u00bb custom_padding=\u00bb4px||4px|20px|true|false\u00bb link_option_url=\u00bb#publicaciones\u00bb border_width_all=\u00bb1px\u00bb border_color_all=\u00bb#aebac1″ border_width_top=\u00bb0px\u00bb border_width_right=\u00bb0px\u00bb border_width_left=\u00bb0px\u00bb border_color_left=\u00bb#FF6600″ box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb0px\u00bb box_shadow_blur=\u00bb0px\u00bb locked=\u00bboff\u00bb border_width_left__hover_enabled=\u00bbon|hover\u00bb border_width_left__hover=\u00bb8px\u00bb box_shadow_blur__hover_enabled=\u00bbon\u00bb custom_padding__hover_enabled=\u00bbon|hover\u00bb custom_padding__hover=\u00bb|32px||\u00bb custom_margin__hover=\u00bb|||-8px\u00bb box_shadow_blur__hover=\u00bb40px\u00bb border_color_left__hover_enabled=\u00bbon|hover\u00bb]<\/p>\n
PUBLICACIONES SELECTAS<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=\u00bb4.2.1″ text_font=\u00bb|600|||||||\u00bb text_font_size=\u00bb12px\u00bb text_line_height=\u00bb1.2em\u00bb background_color=\u00bb#ffffff\u00bb module_alignment=\u00bbleft\u00bb custom_margin=\u00bb0px|0px|0px|0px|false|false\u00bb custom_padding=\u00bb4px||4px|20px|true|false\u00bb link_option_url=\u00bb#resumen\u00bb border_width_all=\u00bb1px\u00bb border_color_all=\u00bb#aebac1″ border_width_top=\u00bb0px\u00bb border_width_right=\u00bb0px\u00bb border_width_left=\u00bb0px\u00bb border_color_left=\u00bb#FF6600″ box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb0px\u00bb box_shadow_blur=\u00bb0px\u00bb locked=\u00bboff\u00bb border_width_left__hover_enabled=\u00bbon|hover\u00bb border_width_left__hover=\u00bb8px\u00bb box_shadow_blur__hover_enabled=\u00bbon\u00bb custom_padding__hover_enabled=\u00bbon|hover\u00bb custom_padding__hover=\u00bb|32px||\u00bb custom_margin__hover=\u00bb|||-8px\u00bb box_shadow_blur__hover=\u00bb40px\u00bb border_color_left__hover_enabled=\u00bbon|hover\u00bb]<\/p>\n
RESUMEN CURRICULAR<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=\u00bb4.2.1″ text_font=\u00bb|600|||||||\u00bb text_font_size=\u00bb12px\u00bb text_line_height=\u00bb1.2em\u00bb background_color=\u00bb#ffffff\u00bb module_alignment=\u00bbleft\u00bb custom_margin=\u00bb0px|0px|0px|0px|false|false\u00bb custom_padding=\u00bb4px||4px|20px|true|false\u00bb link_option_url=\u00bb#investigador\u00bb border_width_all=\u00bb1px\u00bb border_color_all=\u00bb#aebac1″ border_width_top=\u00bb0px\u00bb border_width_right=\u00bb0px\u00bb border_width_left=\u00bb0px\u00bb border_color_left=\u00bb#FF6600″ box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb0px\u00bb box_shadow_blur=\u00bb0px\u00bb locked=\u00bboff\u00bb border_width_left__hover_enabled=\u00bbon|hover\u00bb border_width_left__hover=\u00bb8px\u00bb box_shadow_blur__hover_enabled=\u00bbon\u00bb custom_padding__hover_enabled=\u00bbon|hover\u00bb custom_padding__hover=\u00bb|32px||\u00bb custom_margin__hover=\u00bb|||-8px\u00bb box_shadow_blur__hover=\u00bb40px\u00bb border_color_left__hover_enabled=\u00bbon|hover\u00bb]<\/p>\n
INVESTIGADOR ASOCIADO<\/p>\n
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L\u00cdDER<\/p>\n
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avarela@unam.mx<\/p>\n
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(52) 44 2238 1032<\/p>\n
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Lab A-03<\/p>\n
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CURRICULUM\u00a0<\/p>\n
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Soy Licenciado en Biolog\u00eda por la Universidad Aut\u00f3noma de Nuevo Le\u00f3n y Doctor en Gen\u00e9tica Molecular y Microbiolog\u00eda por la Universidad de Medicina y Odontolog\u00eda de New Jersey.<\/p>\n
Llev\u00e9 a cabo trabajo posdoctoral en neurobiolog\u00eda del desarrollo en el Hospital Guy\u00b4s de la Universidad de Londres y soy actualmente Investigador Titular C del Instituto de Neurobiolog\u00eda de la UNAM, PRIDE C y SNI III.<\/p>\n
Adem\u00e1s he realizado estancias sab\u00e1ticas en el NICHD-NIH y en el Departamento de Biolog\u00eda de Duke University.<\/p>\n
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En mi grupo de investigaci\u00f3n se estudian diversos aspectos de la regulaci\u00f3n molecular del desarrollo del cerebro y su relaci\u00f3n con afecciones del sistema nervioso.<\/p>\n
En una l\u00ednea de trabajo estudiamos los modos y patrones de migraci\u00f3n de tipos neuronales espec\u00edficos en diversas regiones del cerebro en desarrollo. Esto ha permitido la identificaci\u00f3n en la corteza cerebral de poblaciones migratorias nuevas y en el aspecto dorsal del mesenc\u00e9falo una que migra al rombenc\u00e9falo en interacci\u00f3n neurof\u00edlica con axones de las neuronas del n\u00facleo mesencef\u00e1lico del nervio trig\u00e9mino.<\/p>\n
Adem\u00e1s estudiamos el control transcripcional del desarrollo del cerebro. Espec\u00edficamente, analizamos el papel de factores de transcripci\u00f3n en el desarrollo de diversas estructuras del prosenc\u00e9falo y de manera global analizamos la regulaci\u00f3n transcripcional del desarrollo temprano del telenc\u00e9falo del rat\u00f3n y del pollo. Esto se hace con el fin de entender los mecanismos ontogen\u00e9ticos conservados o divergentes que subyacen la divergencia morfol\u00f3gica tan marcada que se observa en el telenc\u00e9falo adulto de estos dos grupos de vertebrados. Estos estudios han revelado redes de regulaci\u00f3n espec\u00edficas en cada especie y han implicado a reguladores de la cromatina en la regulaci\u00f3n temprana del desarrollo del telenc\u00e9falo que tambi\u00e9n han sido ligados a afecciones neurol\u00f3gicas en humanos.<\/p>\n
Utilizando datos gen\u00f3micos y transcript\u00f3micos disponibles p\u00fablicamente, tambi\u00e9n estudiamos los procesos biol\u00f3gicos relacionados con la muerte celular y su relevancia en las enfermedades neurodegenerativas. Nuestro objetivo es delinear m\u00f3dulos gen\u00e9ticos compuestos de muerte celular que se alteren con la neurodegeneraci\u00f3n para comprender c\u00f3mo est\u00e1n regulados e identificar biomarcadores tempranos de enfermedad y objetivos terap\u00e9uticos.<\/p>\n
En estudios recientes hemos iniciado el an\u00e1lisis de la carga de variantes en el genoma mitocondrial en ratones y humanos sanos y su relaci\u00f3n con enfermedades neuromusculares en humanos.<\/p>\n
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Utilizando datos gen\u00f3micos y transcript\u00f3micos disponibles p\u00fablicamente, tambi\u00e9n estudiamos los procesos biol\u00f3gicos relacionados con la muerte celular y su relevancia en las enfermedades neurodegenerativas.<\/p>\n
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Amer S, Alsayegh F, Mashaal Z, Mohamed S, Shawa N, Rajan K, Ahmed SBM.Mol Med Rep. 2019.<\/p>\n
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P\u00e1gina del grupo
ORCID
ResearchGate
Tweeter acad\/cientif
Blog acad\/cientif.
etc..<\/p>\n
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[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00bb1_4,1_4,1_2″ use_custom_gutter=\u00bbon\u00bb gutter_width=\u00bb1″ make_equal=\u00bbon\u00bb module_id=\u00bbresumen\u00bb _builder_version=\u00bb4.2.1″ background_color=\u00bb#ffffff\u00bb background_image=\u00bbhttp:\/\/www.inb.unam.mx\/wp-content\/uploads\/2019\/09\/background-inb-4.png\u00bb width=\u00bb90%\u00bb max_width=\u00bb90%\u00bb module_alignment=\u00bbcenter\u00bb custom_margin=\u00bb-25px|auto||auto||\u00bb custom_padding=\u00bb0px||25px||false|false\u00bb border_color_bottom=\u00bb#ff6600″][et_pb_column type=\u00bb1_4″ _builder_version=\u00bb4.2.1″][\/et_pb_column][et_pb_column type=\u00bb1_4″ _builder_version=\u00bb4.2.1″][et_pb_text _builder_version=\u00bb4.2.1″ text_font=\u00bb|600|||||||\u00bb text_font_size=\u00bb18px\u00bb custom_padding=\u00bb0px|||20px|false|false\u00bb]<\/p>\n
Vujaykumar Yogesh Muley<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=\u00bb4.2.1″ custom_padding=\u00bb0px|||20px|false|false\u00bb]<\/p>\n
vijay.muley@gmail.com<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=\u00bb4.2.1″ text_font=\u00bb|600|||||||\u00bb custom_padding=\u00bb0px|||20px|false|false\u00bb]<\/p>\n
(52) 44 2223 1032<\/p>\n
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CURRICULUM<\/p>\n
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El Dr. Muley tiene dos maestr\u00edas, una en biotecnolog\u00eda y otra en bioinform\u00e1tica y un doctorado en Bioinform\u00e1tica, todos de institutos nacionales reconocidos en la India. Ha trabajado como investigador independiente y profesor asistente en Alemania, Irlanda e India en investigaciones centradas en la organizaci\u00f3n, expresi\u00f3n y regulaci\u00f3n de procesos biol\u00f3gicos a escala del genoma. Actualmente trabaja como Investigador Asociado C (Investigador Asociado C) en el Instituto de Neurobiolog\u00eda, UNAM.<\/p>\n
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El Dr. Muley estudia m\u00f3dulos gen\u00e9ticos que controlan procesos y rasgos fenot\u00edpicos de importancia biol\u00f3gica, biom\u00e9dica y agr\u00edcola utilizando datos gen\u00f3micos y transcript\u00f3micos disponibles p\u00fablicamente mediante la aplicaci\u00f3n de t\u00e9cnicas computacionales de vanguardia.<\/p>\n
Est\u00e1 interesado en los procesos biol\u00f3gicos relacionados con la muerte celular y su relevancia en las enfermedades neurodegenerativas. Las c\u00e9lulas en un organismo multicelular tienen mecanismos de vigilancia de alta fidelidad que controlan la divisi\u00f3n, diferenciaci\u00f3n o muerte. El equilibrio entre estos procesos asegura la estricta regulaci\u00f3n del n\u00famero de c\u00e9lulas dentro de un organismo desde el comienzo de la vida hasta la muerte. Alteraciones en las v\u00edas de muerte celular pueden causar grandes estragos y perturbar la homeostasis del desarrollo y del organismo. Muchas enfermedades cr\u00f3nicas y del desarrollo, incluida la neurodegeneraci\u00f3n, se remontan a defectos en los genes que influyen en la muerte celular.<\/p>\n
Nuestro inter\u00e9s es delinear m\u00f3dulos gen\u00e9ticos compuestos por genes de muerte celular que se ven afectados por la neurodegeneraci\u00f3n y comprender c\u00f3mo est\u00e1n regulados para identificar biomarcadores tempranos de enfermedades y blancos terap\u00e9uticos. El desarrollo embrionario del sistema nervioso es otro inter\u00e9s de nuestro grupo. Algunos de nuestros hallazgos recientes proporcionan evidencia convincente del origen de trastornos neuropsiqui\u00e1tricos en alteraciones del desarrollo de la corteza cerebral. El an\u00e1lisis transcript\u00f3mico comparativo de los datos derivados de varios tejidos de etapas embrionarias tempranas y tard\u00edas tambi\u00e9n es un \u00e1rea activa de investigaci\u00f3n en nuestro grupo. Este es un intento de comprender c\u00f3mo las v\u00edas reguladoras y de se\u00f1alizaci\u00f3n aseguran el desarrollo embrionario adecuado de tejidos y \u00f3rganos. El grupo de investigaci\u00f3n est\u00e1 igualmente interesado en comprender la regulaci\u00f3n de las v\u00edas de respuesta a plegamiento alterado de prote\u00ednas.<\/p>\n
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Utilizando datos gen\u00f3micos y transcript\u00f3micos disponibles p\u00fablicamente, tambi\u00e9n estudiamos los procesos biol\u00f3gicos relacionados con la muerte celular y su relevancia en las enfermedades neurodegenerativas.<\/p>\n
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P\u00e1gina del grupo
ORCID
ResearchGate
Tweeter acad\/cientif
Blog acad\/cientif.
etc..<\/p>\n
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Carlos Lozano Flores<\/p>\n
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lozancarlos@yahoo.com<\/p>\n
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(52) 44 2238 1032<\/p>\n
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Lleva a cabo labores de apoyo a la investigaci\u00f3n y formaci\u00f3n de estudiantes del grupo. Tiene a su cargo labores experimentales en embriolog\u00eda experimental y biolog\u00eda molecular. Adem\u00e1s supervisa el funcionamiento \u00f3ptimo del equipamiento del laboratorio y se encarga de la requisici\u00f3n de insumos para el laboratorio.<\/p>\n
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Kenya Contreras Ram\u00edrez<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=\u00bb4.2.1″ custom_padding=\u00bb0px|||20px|false|false\u00bb]<\/p>\n
kenyalicora@gmail.com<\/p>\n
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(52) 44 2238 1032<\/p>\n
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Estudia la din\u00e1mica mutacional en el genoma mitocondrial en ratones y humanos.<\/p>\n
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Fernando Soto<\/p>\n
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fernando_jsb@hotmail.com<\/p>\n
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(52) 44 2238 1032<\/p>\n
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Estudia la plasticidad gen\u00f3mica en c\u00e9lulas som\u00e1ticas de rat\u00f3n.<\/p>\n
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